Concise and Straightforward Asymmetric Synthesis of a Cyclic Natural Hydroxy-Amino Acid
An enantioselective total synthesis Camera Package of the natural amino acid (2S,4R,5R)-4,5-di-hydroxy-pipecolic acid starting from D-glucoheptono-1, 4-lactone is presented.The best sequence employed as a key step the intramolecular nucleophilic displacement by an amino function of a 6-O-p-toluene-sulphonyl derivative of Toy Pony Accessories a meth